Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.
Introduction
Recently, it absolutely was reported that the new salt (Na)/potassium (K) ratio try for the blood pressure (BP) in a cross-sectional studies [step 1,dos,3,4]. This can be requested given that high Na and you will K consumption is actually recognized as related to high and you can low BP https://datingranking.net/tr/eharmony-inceleme/, correspondingly [5,6,7]. Likewise, research has become held into the reference philosophy and facts causing the new Na/K proportion previously seasons [8, 9].
Sodium/potassium ratio change are from the blood pressure changes: probability of populace method for sodium/potassium proportion loss of health checkup
Within the a residential district function, it is sometimes complicated for all of us to assess the actual Na consumption just like the Na intake is traditionally reviewed by twenty-four-h pee range. Even though multiple equations getting estimating Na intake or K intake having fun with relaxed room pee have been recently oriented, such equations are not direct sufficient to promote opinions on the anybody [ten,11,12]. Also, because the picture demands computing Na, K, and you may creatinine account inside the a lab, it entails few weeks to get the results for people. Even if members realize that sodium protection is made for minimizing BP, he’s no way of assessing the Na peak.
Has just, a good Na/K ratio thinking-keeping track of product playing with spot urine is actually mainly based . Although it did not gauge the genuine Na intake level, it does provide opinions regarding your urinary Na/K equilibrium within minutes. Furthermore, a keen interventional otherwise observational data with this monitor recommended this could be a helpful device in order to guess the new urinary Na/K proportion [thirteen, 14].
For this reason, although we haven’t any solution to assess the Na/K ratio inside the health checkup configurations, we considered that assessing the newest urinary Na/K ratio in a healthcare checkup site may have the possibility to add feedback towards the standard inhabitants regarding their Na/K proportion that will have an impact on feeling change, improvement in step, Na/K ratio avoidance, and BP prevention. Contained in this investigation, i examined perhaps the urinary Na/K proportion alter mentioned towards the Na/K ratio dimension device is actually associated with the BP changes independent away from confounding facts such body mass index (BMI) changes and change inside the liquor consumption and you will compared the fresh new BP level and you may urinary Na/K proportion on neighborhood peak.